Introduction to Epithelial Mesenchymal Transition (EMT)
EMT is thought to be a marker of tumor progression, with tumors that express mesenchymal markers having a greater tendency to be invasive and metastasize than those tumors only expressing epithelial markers. Tumors expressing mesenchymal markers are thought to have a worse prognosis than tumors expressing epithelial markers.
OSI’s Oncology research is focused on understanding the science of EMT in solid tumors in order to develop effective and safe mechanism-based therapeutic agents.
Epithelial Mesenchymal Transition PresentationFor more information on Molecular Targeted Therapies in EMT, please contact Medical Information. |
At OSI, we strive to be at the forefront of the war against cancer by arming patients with an arsenal of tools to help them manage their disease and live productive lives. Our success is based on our ability to discover and develop molecular targeted therapies that enable a sea change in how cancer patients are treated.
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Our research organization is focused on the discovery of novel small molecule compounds targeted against the underlying molecular mechanisms of the pathogenesis of cancer. Our strategy is to develop mechanism-based approaches to drug discovery directed at the processes underlying the role of the Epithelial Mesenchymal Transition (EMT) in the development of cancer.
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